توضیحات

سالسليك اسيد 100 گرم كد 100631 كمپاني مرك آلمان

1.00631 SAFC

Salicylic acid

EMPROVE^® ESSENTIAL Ph Eur,BP,USP

Synonym: 2-Hydroxybenzoic acid, Salicylic acid

• CAS Number 69-72-7
• Empirical Formula (Hill Notation) C₇H₆O₃
• Molecular Weight 138.12
•  MDL number MFCD00002439
•  EC Index Number 200-712-3
  

  Analysis Note

  Assay (acidimetric; calculated on dried substance): 99.5 – 100.5 %
  Assay (HPLC, calc.on dried substance): 98.0 – 102.0 %
  Identity: passes test
  Appearance of solution (10 %; ethanol 96 %): passes test
  Chloride (Cl): ≤ 0.0100 %
  Sulfate (SO₄): ≤ 0.0200 %
  Related substances / HPLC (EP)(4-Hydroxybenzoic acid): ≤ 0.1 %
  Related substances / HPLC (EP)(4-Hydroxyisophthalic acid): ≤ 0.05 %
  Related substances / HPLC (EP)(Phenol): ≤ 0.02 %
  Related substances / HPLC (EP)(Largest unspecified impurity): ≤ 0.05 %
  Related substances / HPLC (EP) (Sum of all impurities): ≤ 0.2 %
  Related substances / HPLC (USP)(4-Hydroxybenzoic acid): ≤ 0.1 %
  Related substances / HPLC (USP)(4-Hydroxyisophthalic acid): ≤ 0.05 %
  Related substances / HPLC (USP)(Phenol): ≤ 0.02 %
  Related substances / HPLC (USP)(Largest unspecified impurity): ≤ 0.05 %
  Related substances / HPLC (USP)(Sum of all impurities): ≤ 0.2 %
  Residual solvents (ICH Q3C): excluded by manufacturing process
  Sulfated ash: ≤ 0.05 %
  Loss on drying: ≤ 0.5 %
  Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
  corresponds to Ph Eur, BP, USP